When I was watching "The Hangover" (which you can hear Eric and me discuss here!) saw one of these "God bless them, they're still trying" actors. At the end, a woman appears as a character's wife and I instantly recognized her. Her name is Gillian Vigman and her three movie credits are pretty impressive for someone you'd probably never give a second look.
Gillian was one of the speed daters Steve Carell talks to in "40 Year Old Virgin" (she was the "Are you f*cking retarded?" one). Then she was one of the interviewers in "Step Brothers" ("You shouldn't tell the person interviewing you to shut their mouths"). Finally, she was in "The Hangover" (no lines).